The Effect of Replens on Vaginal Cytology in the Treatment of Postmenopausal Atrophy: Cytomorphology Versus Computerised Cytometry.
(2002) J Clin Pathol. Jun;55(6):446-51. Van der Laak JA, de Bie LM, de Leeuw H, de Wilde PC, Hanselaar AG.
After the menopause decreased concentrations of oestrogen may result in insufficient maturation of the vaginal epithelium, which can lead to a range of vaginal discomforts. This state vaginal atrophy may be treated with oestrogen replacement treatment. Replens, a non-hormonal alternative to oestrogen replacement treatment has been shown to be effective in relieving symptoms to vaginal atrophy in previous studies.